The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group

Alberto Costa, Thomas Bak, Paolo Caffarra, Carlo Caltagirone, Mathieu Ceccaldi, Fabienne Collette, Sebastian Crutch, Sergio Della Sala, Jean François Démonet, Bruno Dubois, Emrah Duzel, Peter Nestor, Sokratis G. Papageorgiou, Eric Salmon, Sietske Sikkes, Pietro Tiraboschi, Wiesje M. Van Der Flier, Pieter Jelle Visser, Stefano F. Cappa

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a "big data" common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries.

Original languageEnglish
Article number27
JournalAlzheimer's Research and Therapy
Volume9
Issue number1
DOIs
Publication statusPublished - 17 Apr 2017

Cite this

Costa, Alberto ; Bak, Thomas ; Caffarra, Paolo ; Caltagirone, Carlo ; Ceccaldi, Mathieu ; Collette, Fabienne ; Crutch, Sebastian ; Della Sala, Sergio ; Démonet, Jean François ; Dubois, Bruno ; Duzel, Emrah ; Nestor, Peter ; Papageorgiou, Sokratis G. ; Salmon, Eric ; Sikkes, Sietske ; Tiraboschi, Pietro ; Van Der Flier, Wiesje M. ; Visser, Pieter Jelle ; Cappa, Stefano F. / The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe : Consensus document of the Joint Program for Neurodegenerative Diseases Working Group. In: Alzheimer's Research and Therapy. 2017 ; Vol. 9, No. 1.
@article{784b0bcfd94d44d78ef086a3c12a7afd,
title = "The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group",
abstract = "Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a {"}big data{"} common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries.",
keywords = "Behavioural assessment, Cognitive assessment, European research, Longitudinal studies, Neurodegenerative dementia, Neuropsychological tests",
author = "Alberto Costa and Thomas Bak and Paolo Caffarra and Carlo Caltagirone and Mathieu Ceccaldi and Fabienne Collette and Sebastian Crutch and {Della Sala}, Sergio and D{\'e}monet, {Jean Fran{\cc}ois} and Bruno Dubois and Emrah Duzel and Peter Nestor and Papageorgiou, {Sokratis G.} and Eric Salmon and Sietske Sikkes and Pietro Tiraboschi and {Van Der Flier}, {Wiesje M.} and Visser, {Pieter Jelle} and Cappa, {Stefano F.}",
year = "2017",
month = "4",
day = "17",
doi = "10.1186/s13195-017-0254-x",
language = "English",
volume = "9",
journal = "Alzheimer's Research & Therapy",
issn = "1758-9193",
publisher = "BioMed Central",
number = "1",

}

Costa, A, Bak, T, Caffarra, P, Caltagirone, C, Ceccaldi, M, Collette, F, Crutch, S, Della Sala, S, Démonet, JF, Dubois, B, Duzel, E, Nestor, P, Papageorgiou, SG, Salmon, E, Sikkes, S, Tiraboschi, P, Van Der Flier, WM, Visser, PJ & Cappa, SF 2017, 'The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: Consensus document of the Joint Program for Neurodegenerative Diseases Working Group' Alzheimer's Research and Therapy, vol. 9, no. 1, 27. https://doi.org/10.1186/s13195-017-0254-x

The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe : Consensus document of the Joint Program for Neurodegenerative Diseases Working Group. / Costa, Alberto; Bak, Thomas; Caffarra, Paolo; Caltagirone, Carlo; Ceccaldi, Mathieu; Collette, Fabienne; Crutch, Sebastian; Della Sala, Sergio; Démonet, Jean François; Dubois, Bruno; Duzel, Emrah; Nestor, Peter; Papageorgiou, Sokratis G.; Salmon, Eric; Sikkes, Sietske; Tiraboschi, Pietro; Van Der Flier, Wiesje M.; Visser, Pieter Jelle; Cappa, Stefano F.

In: Alzheimer's Research and Therapy, Vol. 9, No. 1, 27, 17.04.2017.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe

T2 - Consensus document of the Joint Program for Neurodegenerative Diseases Working Group

AU - Costa, Alberto

AU - Bak, Thomas

AU - Caffarra, Paolo

AU - Caltagirone, Carlo

AU - Ceccaldi, Mathieu

AU - Collette, Fabienne

AU - Crutch, Sebastian

AU - Della Sala, Sergio

AU - Démonet, Jean François

AU - Dubois, Bruno

AU - Duzel, Emrah

AU - Nestor, Peter

AU - Papageorgiou, Sokratis G.

AU - Salmon, Eric

AU - Sikkes, Sietske

AU - Tiraboschi, Pietro

AU - Van Der Flier, Wiesje M.

AU - Visser, Pieter Jelle

AU - Cappa, Stefano F.

PY - 2017/4/17

Y1 - 2017/4/17

N2 - Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a "big data" common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries.

AB - Cognitive, behavioural, and functional assessment is crucial in longitudinal studies of neurodegenerative dementias (NDD). Central issues, such as the definition of the study population (asymptomatic, at risk, or individuals with dementia), the detection of change/decline, and the assessment of relevant outcomes depend on quantitative measures of cognitive, behavioural, and functional status. Currently, we are far from having available reliable protocols and tools for the assessment of dementias in Europe. The main problems are the heterogeneity of the tools used across different European countries, the lack of standardisation of administration and scoring methods across centres, and the limited information available about the psychometric properties of many tests currently in widespread use. This situation makes it hard to compare results across studies carried out in different centres, thus hampering research progress, in particular towards the contribution to a "big data" common data set. We present here the results of a project funded by the Joint Program for Neurodegenerative Diseases (JPND) and by the Italian Ministry of Health. The project aimed at providing a consensus framework for the harmonisation of assessment tools to be applied to research in neurodegenerative disorders affecting cognition across Europe. A panel of European experts reviewed the current methods of neuropsychological assessment, identified pending issues, and made recommendations for the harmonisation of neuropsychological assessment of neurodegenerative dementias in Europe. A consensus was achieved on the general recommendations to be followed in developing procedures and tools for neuropsychological assessment, with the aim of harmonising tools and procedures to achieve more reliable data on the cognitive-behavioural examination. The results of this study should be considered as a first step to enhancing a common view and practise on NDD assessment across European countries.

KW - Behavioural assessment

KW - Cognitive assessment

KW - European research

KW - Longitudinal studies

KW - Neurodegenerative dementia

KW - Neuropsychological tests

UR - http://www.scopus.com/inward/record.url?scp=85018507140&partnerID=8YFLogxK

U2 - 10.1186/s13195-017-0254-x

DO - 10.1186/s13195-017-0254-x

M3 - Review article

VL - 9

JO - Alzheimer's Research & Therapy

JF - Alzheimer's Research & Therapy

SN - 1758-9193

IS - 1

M1 - 27

ER -