Although highly prevalent, motor syndromes in psychiatry and motor side effects of psychopharmacologic agents remain understudied. Catatonia is a syndrome with specific motor abnormalities that can be seen in the context of a variety of psychiatric and somatic conditions. The neuroleptic malignant syndrome is a lethal variant, induced by antipsychotic drugs. Therefore, antipsychotics should be used with caution in the presence of catatonic signs. Antipsychotics and other dopamine-antagonist drugs can also cause motor side effects such as akathisia, (tardive) dyskinesia, and dystonia. These syndromes share a debilitating impact on the functioning and well-being of patients. To reduce the risk of inducing these side effects, a balanced and well-advised prescription of antipsychotics is of utmost importance. Clinicians should be able to recognize motor side effects and be knowledgeable of the different treatment modalities.
|Title of host publication||Handbook of Clinical Neurology|
|Publication status||Published - 2019|
|Name||Handbook of Clinical Neurology|
Sienaert, P., van Harten, P., & Rhebergen, D. (2019). The psychopharmacology of catatonia, neuroleptic malignant syndrome, akathisia, tardive dyskinesia, and dystonia. In Handbook of Clinical Neurology (Vol. 165, pp. 415-428). (Handbook of Clinical Neurology). Elsevier B.V.. https://doi.org/10.1016/B978-0-444-64012-3.00025-3