The reduced folate/methotrexate carrier and a membrane-associated folate binding protein as transport routes for novel antifolates: structure-activity relationships

G Jansen; G R Westerhof; J H Schornagel; A L Jackman; F T Boyle

The reduced folate/methotrexate carrier and a membrane-associated folate binding protein as transport routes for novel antifolates: structure-activity relationships

G Jansen, G R Westerhof, J H Schornagel, A L Jackman, F T Boyle

Research output: Contribution to journal › Article › Academic

Original language	English
Pages (from-to)	767-70
Number of pages	4
Journal	Advances in Experimental Medicine and Biology
Volume	338
Publication status	Published - 1993

Cite this

@article{cc112c9745dd4b0e8f48a6d1bd06e66a,

title = "The reduced folate/methotrexate carrier and a membrane-associated folate binding protein as transport routes for novel antifolates: structure-activity relationships",

keywords = "Animals, Biological Transport, Carrier Proteins/metabolism, Folate Receptors, GPI-Anchored, Folic Acid Antagonists/metabolism, Kinetics, Leukemia L1210/metabolism, Mice, Quinazolines/chemistry, Receptors, Cell Surface/metabolism, Structure-Activity Relationship, Thymidylate Synthase/antagonists & inhibitors, Tumor Cells, Cultured",

author = "G Jansen and Westerhof, {G R} and Schornagel, {J H} and Jackman, {A L} and Boyle, {F T}",

year = "1993",

language = "English",

volume = "338",

pages = "767--70",

journal = "Advances in Experimental Medicine and Biology",

issn = "0065-2598",

publisher = "Springer New York",

}

The reduced folate/methotrexate carrier and a membrane-associated folate binding protein as transport routes for novel antifolates : structure-activity relationships. / Jansen, G; Westerhof, G R; Schornagel, J H; Jackman, A L; Boyle, F T.

In: Advances in Experimental Medicine and Biology, Vol. 338, 1993, p. 767-70.

Research output: Contribution to journal › Article › Academic

TY - JOUR

T1 - The reduced folate/methotrexate carrier and a membrane-associated folate binding protein as transport routes for novel antifolates

T2 - structure-activity relationships

AU - Jansen, G

AU - Westerhof, G R

AU - Schornagel, J H

AU - Jackman, A L

AU - Boyle, F T

PY - 1993

Y1 - 1993

KW - Animals

KW - Biological Transport

KW - Carrier Proteins/metabolism

KW - Folate Receptors, GPI-Anchored

KW - Folic Acid Antagonists/metabolism

KW - Kinetics

KW - Leukemia L1210/metabolism

KW - Mice

KW - Quinazolines/chemistry

KW - Receptors, Cell Surface/metabolism

KW - Structure-Activity Relationship

KW - Thymidylate Synthase/antagonists & inhibitors

KW - Tumor Cells, Cultured

M3 - Article

C2 - 8304225

VL - 338

SP - 767

EP - 770

JO - Advances in Experimental Medicine and Biology

JF - Advances in Experimental Medicine and Biology

SN - 0065-2598

ER -