The relationship between cognitions and symptoms in obsessive-compulsive disorder

Lee Tibi, Patricia van Oppen, Anton J.L.M. van Balkom, Merijn Eikelenboom, Gert Jan Hendriks, Gideon E. Anholt

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background The cognitive theory of obsessive-compulsive disorder (OCD) ascertains that catastrophic (mis)interpretations of normally occurring intrusive thoughts are related to the maintenance of OCD. Nonetheless, findings supporting the relationship between cognitive biases and OCD symptoms are largely inconsistent. In the present study we examined the relationship between OCD cognitions and symptoms among 382 OCD patients participating in the longitudinal Netherlands Obsessive Compulsive Disorder Association (NOCDA) study. Methods OCD cognitions and OC, anxiety and depressive symptoms were assessed using self-report questionnaires at baseline and at two-year follow-up. Baseline multiple regression analyses assessed the specificity of OC cognitions to OCD symptoms. Cross-lagged analyses examined whether cognitions predict OCD symptoms at two-year follow up. Results Baseline analyses demonstrated significant relationships between comorbid anxiety, depressive severity and OC cognitions, adjusted for OCD symptoms (β =.283, p <.001 and β =.246, p <.001, respectively). OCD severity adjusted for comorbid symptoms was unrelated to cognitions at baseline (β =.040, p = n.s). Unique associations were found between cognitions and two OCD symptom subtypes (Impulses: β =.215, p <.001; Rumination/doubting: β =.205, p <.001). Longitudinal analyses yielded non-significant associations between OCD cognitions and symptom severity. Prospective analyses of cognitions and OCD symptom subtypes yielded significant effects for both bidirectional and unidirectional associations (β =.11–.16, p <.05). Limitations Given the naturalistic design of the study, we did not assess therapeutic interventions between baseline and follow-up. Conclusions Results only partially concord with the predictions of the cognitive theory of OCD. Future studies should focus on mechanisms alternative to cognitions when investigating the course of OCD.

Original languageEnglish
Pages (from-to)495-502
Number of pages8
JournalJournal of Affective Disorders
Volume225
DOIs
Publication statusPublished - 1 Jan 2018

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