The role of spinal cord imaging in the diagnosis of multiple sclerosis

Jessica M. Nielsen*, Frederik Barkhof, Bob W. van Oosten, Chris H. Polman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Background: A 29-year-old male presented with fluctuating but progressive sensory disturbances comprising tingling and dysesthesia in his right leg. MRI of the brain showed white matter lesions initially thought to be caused by multiple sclerosis. Investigations: Neurological examination, cerebrospinal fluid examination, laboratory blood testing, brain and spinal MRI scans. Diagnosis: Spinal cord schwannoma. Management: Surgical removal of the schwannoma. An algorithm is provided that clarifies the appropriate MRI work-up for cases where the clinical presentation is suggestive of multiple sclerosis.

Original languageEnglish
Pages (from-to)283-286
Number of pages4
JournalNature Clinical Practice Neurology
Issue number5
Publication statusPublished - 1 May 2006

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