Comparison of the partial sequences of the human βB2-1- and βB2-2-crystallin genes with orthologous rat or calf sequences shows that the fourth exon sequence of the human βB2-2 gene contains a one triplet deletion and a mutated splice acceptor site. No transcripts from the βB2-2-crystallin gene could be detected in the human lens. These data suggest that the human βB2-2-crystallin gene is a pseudogene.
|Number of pages||4|
|Journal||Experimental Eye Research|
|Publication status||Published - May 1992|