The Sleeping Cerebellum

Cathrin B Canto, Yoshiyuki Onuki, Bastiaan Bruinsma, Ysbrand D van der Werf, Chris I De Zeeuw

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

We sleep almost one-third of our lives and sleep plays an important role in critical brain functions like memory formation and consolidation. The role of sleep in cerebellar processing, however, constitutes an enigma in the field of neuroscience; we know little about cerebellar sleep-physiology, cerebro-cerebellar interactions during sleep, or the contributions of sleep to cerebellum-dependent memory consolidation. Likewise, we do not understand why cerebellar malfunction can lead to changes in the sleep-wake cycle and sleep disorders. In this review, we evaluate how sleep and cerebellar processing may influence one another and highlight which scientific routes and technical approaches could be taken to uncover the mechanisms underlying these interactions.

Original languageEnglish
Pages (from-to)309-323
Number of pages15
JournalTrends in Neurosciences
Volume40
Issue number5
DOIs
Publication statusPublished - May 2017

Cite this

Canto, C. B., Onuki, Y., Bruinsma, B., van der Werf, Y. D., & De Zeeuw, C. I. (2017). The Sleeping Cerebellum. Trends in Neurosciences, 40(5), 309-323. https://doi.org/10.1016/j.tins.2017.03.001
Canto, Cathrin B ; Onuki, Yoshiyuki ; Bruinsma, Bastiaan ; van der Werf, Ysbrand D ; De Zeeuw, Chris I. / The Sleeping Cerebellum. In: Trends in Neurosciences. 2017 ; Vol. 40, No. 5. pp. 309-323.
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Canto, CB, Onuki, Y, Bruinsma, B, van der Werf, YD & De Zeeuw, CI 2017, 'The Sleeping Cerebellum' Trends in Neurosciences, vol. 40, no. 5, pp. 309-323. https://doi.org/10.1016/j.tins.2017.03.001

The Sleeping Cerebellum. / Canto, Cathrin B; Onuki, Yoshiyuki; Bruinsma, Bastiaan; van der Werf, Ysbrand D; De Zeeuw, Chris I.

In: Trends in Neurosciences, Vol. 40, No. 5, 05.2017, p. 309-323.

Research output: Contribution to journalReview articleAcademicpeer-review

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T1 - The Sleeping Cerebellum

AU - Canto, Cathrin B

AU - Onuki, Yoshiyuki

AU - Bruinsma, Bastiaan

AU - van der Werf, Ysbrand D

AU - De Zeeuw, Chris I

N1 - Copyright © 2017 Elsevier Ltd. All rights reserved.

PY - 2017/5

Y1 - 2017/5

N2 - We sleep almost one-third of our lives and sleep plays an important role in critical brain functions like memory formation and consolidation. The role of sleep in cerebellar processing, however, constitutes an enigma in the field of neuroscience; we know little about cerebellar sleep-physiology, cerebro-cerebellar interactions during sleep, or the contributions of sleep to cerebellum-dependent memory consolidation. Likewise, we do not understand why cerebellar malfunction can lead to changes in the sleep-wake cycle and sleep disorders. In this review, we evaluate how sleep and cerebellar processing may influence one another and highlight which scientific routes and technical approaches could be taken to uncover the mechanisms underlying these interactions.

AB - We sleep almost one-third of our lives and sleep plays an important role in critical brain functions like memory formation and consolidation. The role of sleep in cerebellar processing, however, constitutes an enigma in the field of neuroscience; we know little about cerebellar sleep-physiology, cerebro-cerebellar interactions during sleep, or the contributions of sleep to cerebellum-dependent memory consolidation. Likewise, we do not understand why cerebellar malfunction can lead to changes in the sleep-wake cycle and sleep disorders. In this review, we evaluate how sleep and cerebellar processing may influence one another and highlight which scientific routes and technical approaches could be taken to uncover the mechanisms underlying these interactions.

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DO - 10.1016/j.tins.2017.03.001

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Canto CB, Onuki Y, Bruinsma B, van der Werf YD, De Zeeuw CI. The Sleeping Cerebellum. Trends in Neurosciences. 2017 May;40(5):309-323. https://doi.org/10.1016/j.tins.2017.03.001