The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule

J.I.M. van Uhm; G.W. Visser; M.J. van der Schans; A.A. Geldof; E.J. Meuleman; J.A. Nieuwenhuijzen

doi:10.1186/s13550-015-0083-5

The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule

J.I.M. van Uhm, G.W. Visser, M.J. van der Schans, A.A. Geldof, E.J. Meuleman, J.A. Nieuwenhuijzen

Research output: Contribution to journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Article number	5
Journal	EJNMMI Research
Volume	5
DOIs	https://doi.org/10.1186/s13550-015-0083-5
Publication status	Published - 2015

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10.1186/s13550-015-0083-5

Cite this

@article{12426781afc84aa3927190f3c1fbe2f5,

title = "The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule",

author = "{van Uhm}, J.I.M. and G.W. Visser and {van der Schans}, M.J. and A.A. Geldof and E.J. Meuleman and J.A. Nieuwenhuijzen",

year = "2015",

doi = "10.1186/s13550-015-0083-5",

language = "Undefined/Unknown",

volume = "5",

journal = "EJNMMI Research",

issn = "2191-219X",

publisher = "Springer Berlin",

}

The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule. / van Uhm, J.I.M.; Visser, G.W.; van der Schans, M.J.; Geldof, A.A.; Meuleman, E.J.; Nieuwenhuijzen, J.A.

In: EJNMMI Research, Vol. 5, 5, 2015.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The ultimate radiochemical nightmare: upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule

AU - van Uhm, J.I.M.

AU - Visser, G.W.

AU - van der Schans, M.J.

AU - Geldof, A.A.

AU - Meuleman, E.J.

AU - Nieuwenhuijzen, J.A.

PY - 2015

Y1 - 2015

U2 - 10.1186/s13550-015-0083-5

DO - 10.1186/s13550-015-0083-5

M3 - Article

C2 - 25853011

VL - 5

JO - EJNMMI Research

JF - EJNMMI Research

SN - 2191-219X

M1 - 5

ER -