The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

on behalf of the Executive Committee of the European Society of Human Genetics; the Public and Professional Policy Committee of the European Society of Human Genetics

doi:10.1038/s41431-021-01000-x

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

on behalf of the Executive Committee of the European Society of Human Genetics, the Public and Professional Policy Committee of the European Society of Human Genetics

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Journal	European Journal of Human Genetics
Early online date	2021
DOIs	https://doi.org/10.1038/s41431-021-01000-x
Publication status	E-pub ahead of print - 2021

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10.1038/s41431-021-01000-x

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@article{8d136316900b460e90098f8bd87fcb8b,

title = "The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice",

author = "Francesca Forzano and Olga Antonova and Angus Clarke and {de Wert}, Guido and Sabine Hentze and Yalda Jamshidi and Yves Moreau and Markus Perola and Inga Prokopenko and Andrew Read and Alexandre Reymond and Vigdis Stefansdottir and {van el}, Carla and Maurizio Genuardi and Borut Peterlin and Carla Oliveira and Karin Writzl and Houge, {Gunnar Douzgos} and Christophe Cordier and Heidi Howard and Milan Macek and Melegh, {B. la} and Alvaro Mendes and Dragica Radojkovic and {on behalf of the Executive Committee of the European Society of Human Genetics} and Emmanuelle Rial-Sebbag and {the Public and Professional Policy Committee of the European Society of Human Genetics} and Fiona Ulph and Yalda Jamshidi",

note = "Funding Information: IP has received funding from the World Cancer Research Fund (WCRF UK) and World Cancer Research Fund International (2017/1641), the European Union{\textquoteright}s Horizon 2020 research and innovation programme (LONGITOOLS, H2020-SC1-2019-874739), the Ministry of Science and Higher Education of Russian Federation (075-15-2021-595), Agence Nationale de la Recherche (PreciDIAB, ANR-18-IBHU-0001), the European Union through the “Fonds europ{\'e}en de d{\'e}veloppement regional” (FEDER), the “Conseil R{\'e}gional des Hauts-de-France” (Hauts-de-France Regional Council), and the “M{\'e}tropole Europ{\'e}enne de Lille” (MEL, European Metropolis of Lille).",

year = "2021",

doi = "10.1038/s41431-021-01000-x",

language = "English",

journal = "European Journal of Human Genetics",

issn = "1018-4813",

publisher = "Nature Publishing Group",

}

The use of polygenic risk scores in pre-implantation genetic testing : an unproven, unethical practice. / on behalf of the Executive Committee of the European Society of Human Genetics; the Public and Professional Policy Committee of the European Society of Human Genetics.

In: European Journal of Human Genetics, 2021.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The use of polygenic risk scores in pre-implantation genetic testing

T2 - an unproven, unethical practice

AU - Forzano, Francesca

AU - Antonova, Olga

AU - Clarke, Angus

AU - de Wert, Guido

AU - Hentze, Sabine

AU - Jamshidi, Yalda

AU - Moreau, Yves

AU - Perola, Markus

AU - Prokopenko, Inga

AU - Read, Andrew

AU - Reymond, Alexandre

AU - Stefansdottir, Vigdis

AU - van el, Carla

AU - Genuardi, Maurizio

AU - Peterlin, Borut

AU - Oliveira, Carla

AU - Writzl, Karin

AU - Houge, Gunnar Douzgos

AU - Cordier, Christophe

AU - Howard, Heidi

AU - Macek, Milan

AU - Melegh, B. la

AU - Mendes, Alvaro

AU - Radojkovic, Dragica

AU - on behalf of the Executive Committee of the European Society of Human Genetics

AU - Rial-Sebbag, Emmanuelle

AU - the Public and Professional Policy Committee of the European Society of Human Genetics

AU - Ulph, Fiona

AU - Jamshidi, Yalda

N1 - Funding Information: IP has received funding from the World Cancer Research Fund (WCRF UK) and World Cancer Research Fund International (2017/1641), the European Union’s Horizon 2020 research and innovation programme (LONGITOOLS, H2020-SC1-2019-874739), the Ministry of Science and Higher Education of Russian Federation (075-15-2021-595), Agence Nationale de la Recherche (PreciDIAB, ANR-18-IBHU-0001), the European Union through the “Fonds européen de développement regional” (FEDER), the “Conseil Régional des Hauts-de-France” (Hauts-de-France Regional Council), and the “Métropole Européenne de Lille” (MEL, European Metropolis of Lille).

PY - 2021

Y1 - 2021

UR - http://www.scopus.com/inward/record.url?scp=85121535929&partnerID=8YFLogxK

U2 - 10.1038/s41431-021-01000-x

DO - 10.1038/s41431-021-01000-x

M3 - Article

C2 - 34916614

SN - 1018-4813

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

ER -

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

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