The value of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip prostheses: a meta-analysis

Olivier P P Temmerman, Ide C Heyligers, Gerrit J J Teule, Otto S Hoekstra, Pieter G H M Raijmakers

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

OBJECTIVE: To summarize and compare the diagnostic accuracy of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip arthroplasties.

DESIGN: This meta-analysis was performed using methods described by the Cochrane Methods Group on Systematic Reviews of Screening and Diagnostic Tests. We included original, English-language papers published between January 1975 to October 2004 that examined contrast-enhanced arthrography with or without subtraction for diagnosis of loosening of total hip prostheses. A qualitative and quantitative analysis was performed by two investigators.

RESULTS: With regard to the acetabular component, pooled sensitivity and specificity for contrast arthrography was 70% (95% confidence interval, 52-84) and 74% (95% CI, 53-87), respectively. Subtraction arthrography had a significantly higher sensitivity of 89% (95% CI, 84-93) (p=0.01), with a similar specificity of 76% (95% CI, 68-82). For the femoral component, pooled sensitivity and specificity for contrast arthrography were 63% (95% CI, 53-72) and 78% (95% CI, 68-86). Pooled estimates for subtraction arthrography revealed a significantly higher sensitivity of 86% (95% CI, 74-93) (p=0.003). Specificity was 85% (95% CI, 77-91) and was similar to the data of contrast arthrography (p=0.23).

CONCLUSION: Using the present data we found that the subtraction arthrography is a sensitive technique for detection of loosening of total hip prostheses, offering added value over contrast arthrography, especially for evaluation of the femoral component.

Original languageEnglish
Pages (from-to)113-119
Number of pages7
JournalEuropean Journal of Radiology
Volume56
Issue number1
DOIs
Publication statusPublished - Oct 2005

Cite this

@article{2da04c7d48d94176b4e312c87c49641a,
title = "The value of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip prostheses: a meta-analysis",
abstract = "OBJECTIVE: To summarize and compare the diagnostic accuracy of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip arthroplasties.DESIGN: This meta-analysis was performed using methods described by the Cochrane Methods Group on Systematic Reviews of Screening and Diagnostic Tests. We included original, English-language papers published between January 1975 to October 2004 that examined contrast-enhanced arthrography with or without subtraction for diagnosis of loosening of total hip prostheses. A qualitative and quantitative analysis was performed by two investigators.RESULTS: With regard to the acetabular component, pooled sensitivity and specificity for contrast arthrography was 70{\%} (95{\%} confidence interval, 52-84) and 74{\%} (95{\%} CI, 53-87), respectively. Subtraction arthrography had a significantly higher sensitivity of 89{\%} (95{\%} CI, 84-93) (p=0.01), with a similar specificity of 76{\%} (95{\%} CI, 68-82). For the femoral component, pooled sensitivity and specificity for contrast arthrography were 63{\%} (95{\%} CI, 53-72) and 78{\%} (95{\%} CI, 68-86). Pooled estimates for subtraction arthrography revealed a significantly higher sensitivity of 86{\%} (95{\%} CI, 74-93) (p=0.003). Specificity was 85{\%} (95{\%} CI, 77-91) and was similar to the data of contrast arthrography (p=0.23).CONCLUSION: Using the present data we found that the subtraction arthrography is a sensitive technique for detection of loosening of total hip prostheses, offering added value over contrast arthrography, especially for evaluation of the femoral component.",
keywords = "Adult, Arthrography/methods, Arthroplasty, Replacement, Hip/adverse effects, Contrast Media/administration & dosage, Hip Joint/diagnostic imaging, Hip Prosthesis, Humans, Prosthesis Failure, ROC Curve, Radiographic Image Enhancement/methods, Reproducibility of Results, Sensitivity and Specificity, Subtraction Technique, Systematic literature review, meta analysis (topic)",
author = "Temmerman, {Olivier P P} and Heyligers, {Ide C} and Teule, {Gerrit J J} and Hoekstra, {Otto S} and Raijmakers, {Pieter G H M}",
year = "2005",
month = "10",
doi = "10.1016/j.ejrad.2005.02.008",
language = "English",
volume = "56",
pages = "113--119",
journal = "European Journal of Radiology",
issn = "0720-048X",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

The value of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip prostheses : a meta-analysis. / Temmerman, Olivier P P; Heyligers, Ide C; Teule, Gerrit J J; Hoekstra, Otto S; Raijmakers, Pieter G H M.

In: European Journal of Radiology, Vol. 56, No. 1, 10.2005, p. 113-119.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - The value of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip prostheses

T2 - a meta-analysis

AU - Temmerman, Olivier P P

AU - Heyligers, Ide C

AU - Teule, Gerrit J J

AU - Hoekstra, Otto S

AU - Raijmakers, Pieter G H M

PY - 2005/10

Y1 - 2005/10

N2 - OBJECTIVE: To summarize and compare the diagnostic accuracy of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip arthroplasties.DESIGN: This meta-analysis was performed using methods described by the Cochrane Methods Group on Systematic Reviews of Screening and Diagnostic Tests. We included original, English-language papers published between January 1975 to October 2004 that examined contrast-enhanced arthrography with or without subtraction for diagnosis of loosening of total hip prostheses. A qualitative and quantitative analysis was performed by two investigators.RESULTS: With regard to the acetabular component, pooled sensitivity and specificity for contrast arthrography was 70% (95% confidence interval, 52-84) and 74% (95% CI, 53-87), respectively. Subtraction arthrography had a significantly higher sensitivity of 89% (95% CI, 84-93) (p=0.01), with a similar specificity of 76% (95% CI, 68-82). For the femoral component, pooled sensitivity and specificity for contrast arthrography were 63% (95% CI, 53-72) and 78% (95% CI, 68-86). Pooled estimates for subtraction arthrography revealed a significantly higher sensitivity of 86% (95% CI, 74-93) (p=0.003). Specificity was 85% (95% CI, 77-91) and was similar to the data of contrast arthrography (p=0.23).CONCLUSION: Using the present data we found that the subtraction arthrography is a sensitive technique for detection of loosening of total hip prostheses, offering added value over contrast arthrography, especially for evaluation of the femoral component.

AB - OBJECTIVE: To summarize and compare the diagnostic accuracy of contrast and subtraction arthrography in the assessment of aseptic loosening of total hip arthroplasties.DESIGN: This meta-analysis was performed using methods described by the Cochrane Methods Group on Systematic Reviews of Screening and Diagnostic Tests. We included original, English-language papers published between January 1975 to October 2004 that examined contrast-enhanced arthrography with or without subtraction for diagnosis of loosening of total hip prostheses. A qualitative and quantitative analysis was performed by two investigators.RESULTS: With regard to the acetabular component, pooled sensitivity and specificity for contrast arthrography was 70% (95% confidence interval, 52-84) and 74% (95% CI, 53-87), respectively. Subtraction arthrography had a significantly higher sensitivity of 89% (95% CI, 84-93) (p=0.01), with a similar specificity of 76% (95% CI, 68-82). For the femoral component, pooled sensitivity and specificity for contrast arthrography were 63% (95% CI, 53-72) and 78% (95% CI, 68-86). Pooled estimates for subtraction arthrography revealed a significantly higher sensitivity of 86% (95% CI, 74-93) (p=0.003). Specificity was 85% (95% CI, 77-91) and was similar to the data of contrast arthrography (p=0.23).CONCLUSION: Using the present data we found that the subtraction arthrography is a sensitive technique for detection of loosening of total hip prostheses, offering added value over contrast arthrography, especially for evaluation of the femoral component.

KW - Adult

KW - Arthrography/methods

KW - Arthroplasty, Replacement, Hip/adverse effects

KW - Contrast Media/administration & dosage

KW - Hip Joint/diagnostic imaging

KW - Hip Prosthesis

KW - Humans

KW - Prosthesis Failure

KW - ROC Curve

KW - Radiographic Image Enhancement/methods

KW - Reproducibility of Results

KW - Sensitivity and Specificity

KW - Subtraction Technique

KW - Systematic literature review

KW - meta analysis (topic)

U2 - 10.1016/j.ejrad.2005.02.008

DO - 10.1016/j.ejrad.2005.02.008

M3 - Article

VL - 56

SP - 113

EP - 119

JO - European Journal of Radiology

JF - European Journal of Radiology

SN - 0720-048X

IS - 1

ER -