Tissue engineering in burn scar reconstruction

P. P.M. Van Zuijlen; K. L.M. Gardien; M. E.H. Jaspers; E. J. Bos; D. C. Baas; A. J.M. Van Trier; E. Middelkoop

doi:10.1186/s41038-015-0017-5

Tissue engineering in burn scar reconstruction

P. P.M. Van Zuijlen^*, K. L.M. Gardien, M. E.H. Jaspers, E. J. Bos, D. C. Baas, A. J.M. Van Trier, E. Middelkoop

^*Corresponding author for this work

Plastic, Reconstructive and Hand Surgery

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

Original language	English
Article number	18
Journal	Burns & trauma
Volume	3
Issue number	1
DOIs	https://doi.org/10.1186/s41038-015-0017-5 https://doi.org/10.1186/s41038-015-0017-5
Publication status	Published - 2015

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title = "Tissue engineering in burn scar reconstruction",

abstract = "Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage. ",

keywords = "Burns, Cartilage, Contracture, Reconstruction, Scar, Subcutaneous fat tissue, Substitute, Tissue engineering",

author = "{Van Zuijlen}, {P. P.M.} and Gardien, {K. L.M.} and Jaspers, {M. E.H.} and Bos, {E. J.} and Baas, {D. C.} and {Van Trier}, {A. J.M.} and E. Middelkoop",

note = "Publisher Copyright: {\textcopyright} 2016 The Author(s).",

year = "2015",

doi = "10.1186/s41038-015-0017-5",

language = "English",

volume = "3",

journal = "Burns & trauma",

issn = "2321-3868",

publisher = "Oxford University Press",

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T1 - Tissue engineering in burn scar reconstruction

AU - Van Zuijlen, P. P.M.

AU - Gardien, K. L.M.

AU - Jaspers, M. E.H.

AU - Bos, E. J.

AU - Baas, D. C.

AU - Van Trier, A. J.M.

AU - Middelkoop, E.

PY - 2015

Y1 - 2015

N2 - Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

AB - Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

KW - Burns

KW - Cartilage

KW - Contracture

KW - Reconstruction

KW - Scar

KW - Subcutaneous fat tissue

KW - Substitute

KW - Tissue engineering

UR - http://www.scopus.com/inward/record.url?scp=84994825383&partnerID=8YFLogxK

U2 - 10.1186/s41038-015-0017-5

DO - 10.1186/s41038-015-0017-5

M3 - Review article

C2 - 27574664

VL - 3

JO - Burns & trauma

JF - Burns & trauma

SN - 2321-3868

IS - 1

M1 - 18

ER -

Tissue engineering in burn scar reconstruction

Abstract

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