- Probiotics are defined as 'live micro-organisms that confer a health benefit on the host if administered in adequate amounts'. - There are only limited data in the literature regarding the efficacy and safety of lactobacilli for various gastrointestinal indications in children. - Lactobacillus rhamnosus GG (LGG) has no added value in the treatment of children with functional constipation. - Lactobacilli do seem to be effective in rotavirus diarrhoea. They seem safe and shorten the duration of the diarrhoea by about 1 day. - For the prevention of infectious diarrhoea, lactobacilli are only moderately effective and the clinical relevance is unclear. - There is 1 controlled study in which LGG had a preventive effect on the development of atopic eczema (but not of allergy to cow's milk) in newborn infants.
|Journal||Nederlands Tijdschrift voor Geneeskunde|
|Publication status||Published - 2007|