Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Awarding Institution | - From initial therapy to follow-up
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| Supervisors/Advisors | - van Noorden, Cornelis J. F., Supervisor, External person
- Vandertop, William, Supervisor
- Bleeker, FE, Co-supervisor
- Wilmink, Johanna W., Co-supervisor, External person
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| Award date | 22 Dec 2017 |
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| Print ISBNs | 978-94-6299-812-4 |
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| Publication status | Published - 2017 |
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| Externally published | Yes |
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@phdthesis{5772765082f6413ebd47dc6f9c13d7c1,
title = "Towards personalised medicine for cancer",
abstract = "Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.",
author = "R.J. Molenaar",
year = "2017",
language = "English",
isbn = "978-94-6299-812-4",
school = "From initial therapy to follow-up",
}
TY - THES
T1 - Towards personalised medicine for cancer
AU - Molenaar, R.J.
PY - 2017
Y1 - 2017
N2 - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.
AB - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.
M3 - Research VU University Amsterdam, graduation external
SN - 978-94-6299-812-4
ER -