Towards personalised medicine for cancer

R.J. Molenaar

Towards personalised medicine for cancer

R.J. Molenaar

Research output: Thesis › Research VU University Amsterdam, graduation external

Abstract

Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	From initial therapy to follow-up
Supervisors/Advisors	van Noorden, Cornelis J. F., Supervisor, External person Vandertop, William, Supervisor Bleeker, FE, Co-supervisor Wilmink, Johanna W., Co-supervisor, External person
Award date	22 Dec 2017
Print ISBNs	978-94-6299-812-4
Publication status	Published - 2017
Externally published	Yes

Cite this

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abstract = "Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.",

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N2 - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.

AB - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.

M3 - Research VU University Amsterdam, graduation external

SN - 978-94-6299-812-4

ER -