Towards personalised medicine for cancer

R.J. Molenaar

Research output: ThesisResearch VU University Amsterdam, graduation externalAcademic

Abstract

Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • From initial therapy to follow-up
Supervisors/Advisors
  • van Noorden, Cornelis J. F., Supervisor, External person
  • Vandertop, William, Supervisor
  • Bleeker, FE, Co-supervisor
  • Wilmink, Johanna W., Co-supervisor, External person
Award date22 Dec 2017
Print ISBNs978-94-6299-812-4
Publication statusPublished - 2017
Externally publishedYes

Cite this

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title = "Towards personalised medicine for cancer",
abstract = "Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.",
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Molenaar, RJ 2017, 'Towards personalised medicine for cancer', Doctor of Philosophy, From initial therapy to follow-up.

Towards personalised medicine for cancer. / Molenaar, R.J.

2017.

Research output: ThesisResearch VU University Amsterdam, graduation externalAcademic

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AB - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.

M3 - Research VU University Amsterdam, graduation external

SN - 978-94-6299-812-4

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