Abstract
| Original language | English |
|---|---|
| Qualification | Doctor of Philosophy |
| Awarding Institution |
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| Supervisors/Advisors |
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| Award date | 22 Dec 2017 |
| Print ISBNs | 978-94-6299-812-4 |
| Publication status | Published - 2017 |
| Externally published | Yes |
Cite this
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Towards personalised medicine for cancer. / Molenaar, R.J.
2017.Research output: Thesis › Research VU University Amsterdam, graduation external › Academic
TY - THES
T1 - Towards personalised medicine for cancer
AU - Molenaar, R.J.
PY - 2017
Y1 - 2017
N2 - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.
AB - Overall, the studies described in the present dissertation are aimed at the improvement of personalised medicine strategies for various types of cancer. The studies in parts 1 and 2 describe potential novel therapeutic avenues to treat IDH1/2-mutated cancers and the conditions in which they may have optimal effects. The studies described in part 3 may improve risk/benefit assessments for the application of cytotoxic therapies in an individual patient, and the follow-up after the administration of such cytotoxic therapies. These nuances may ultimately improve personalized treatment and management of cancer.
M3 - Research VU University Amsterdam, graduation external
SN - 978-94-6299-812-4
ER -