Transmission of HIV and AIDS by plasmapheresis for Guillain-Barré Syndrome

Charles A.B. Boucher, Jan de Gans, Rien van Oers, Sven Danner, Goudsmit Jaap*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


A 58-year-old patient suffering from Guillain-Barré syndrome was successfully treated with plasma exchange therapy. Two- and half year later she developed AIDS. The only risk factor of this patient was plasmapheresis and it appeared, retrospectively, that one of the plasma donor samples contained antibodies to HIV. Knowing the exact moment of infection of our patient we documented the transfer of HIV antibodies from donor to patient, a HIV antigen peak two weeks after transmission (reflecting the initial virus replication in the patient) and subsequently the occurrence of patients' HIV antibodies and the reoccurrence of HIV antigen at the moment AIDS was diagnosed.

Original languageEnglish
Pages (from-to)235-236
Number of pages2
JournalClinical Neurology and Neurosurgery
Issue number3
Publication statusPublished - 1988

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