Transmission of HIV and AIDS by plasmapheresis for Guillain-Barré Syndrome

Charles A.B. Boucher; Jan de Gans; Rien van Oers; Sven Danner; Goudsmit Jaap

doi:10.1016/0303-8467(88)90027-3

Transmission of HIV and AIDS by plasmapheresis for Guillain-Barré Syndrome

Charles A.B. Boucher, Jan de Gans, Rien van Oers, Sven Danner, Goudsmit Jaap^*

^*Corresponding author for this work

Internal medicine

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 58-year-old patient suffering from Guillain-Barré syndrome was successfully treated with plasma exchange therapy. Two- and half year later she developed AIDS. The only risk factor of this patient was plasmapheresis and it appeared, retrospectively, that one of the plasma donor samples contained antibodies to HIV. Knowing the exact moment of infection of our patient we documented the transfer of HIV antibodies from donor to patient, a HIV antigen peak two weeks after transmission (reflecting the initial virus replication in the patient) and subsequently the occurrence of patients' HIV antibodies and the reoccurrence of HIV antigen at the moment AIDS was diagnosed.

Original language	English
Pages (from-to)	235-236
Number of pages	2
Journal	Clinical Neurology and Neurosurgery
Volume	90
Issue number	3
DOIs	https://doi.org/10.1016/0303-8467(88)90027-3
Publication status	Published - 1988

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title = "Transmission of HIV and AIDS by plasmapheresis for Guillain-Barr{\'e} Syndrome",

abstract = "A 58-year-old patient suffering from Guillain-Barr{\'e} syndrome was successfully treated with plasma exchange therapy. Two- and half year later she developed AIDS. The only risk factor of this patient was plasmapheresis and it appeared, retrospectively, that one of the plasma donor samples contained antibodies to HIV. Knowing the exact moment of infection of our patient we documented the transfer of HIV antibodies from donor to patient, a HIV antigen peak two weeks after transmission (reflecting the initial virus replication in the patient) and subsequently the occurrence of patients' HIV antibodies and the reoccurrence of HIV antigen at the moment AIDS was diagnosed.",

keywords = "AIDS, Guillain-Barr{\'e} syndrome, HIV, plasmapheresis",

author = "Boucher, {Charles A.B.} and {de Gans}, Jan and {van Oers}, Rien and Sven Danner and Goudsmit Jaap",

year = "1988",

doi = "10.1016/0303-8467(88)90027-3",

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AU - Boucher, Charles A.B.

AU - de Gans, Jan

AU - van Oers, Rien

AU - Danner, Sven

AU - Jaap, Goudsmit

PY - 1988

Y1 - 1988

N2 - A 58-year-old patient suffering from Guillain-Barré syndrome was successfully treated with plasma exchange therapy. Two- and half year later she developed AIDS. The only risk factor of this patient was plasmapheresis and it appeared, retrospectively, that one of the plasma donor samples contained antibodies to HIV. Knowing the exact moment of infection of our patient we documented the transfer of HIV antibodies from donor to patient, a HIV antigen peak two weeks after transmission (reflecting the initial virus replication in the patient) and subsequently the occurrence of patients' HIV antibodies and the reoccurrence of HIV antigen at the moment AIDS was diagnosed.

AB - A 58-year-old patient suffering from Guillain-Barré syndrome was successfully treated with plasma exchange therapy. Two- and half year later she developed AIDS. The only risk factor of this patient was plasmapheresis and it appeared, retrospectively, that one of the plasma donor samples contained antibodies to HIV. Knowing the exact moment of infection of our patient we documented the transfer of HIV antibodies from donor to patient, a HIV antigen peak two weeks after transmission (reflecting the initial virus replication in the patient) and subsequently the occurrence of patients' HIV antibodies and the reoccurrence of HIV antigen at the moment AIDS was diagnosed.

KW - AIDS

KW - Guillain-Barré syndrome

KW - HIV

KW - plasmapheresis

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JO - Clinical Neurology and Neurosurgery

JF - Clinical Neurology and Neurosurgery

SN - 0303-8467

IS - 3

ER -

Transmission of HIV and AIDS by plasmapheresis for Guillain-Barré Syndrome

Abstract

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