Behandeling van patiënten met ernstige glucocorticoïd-refractaire colitis ulcerosa: Ciclosporine of infliximab?

Translated title of the contribution: Treatment of patients with severe glucocorticoid-refractory ulcerative colitis: Cyclosporine or infliximab?

Mark Löwenberg, Nanne K.H. De Boer, Pieter Dewint, Frank Hoentjen*

*Corresponding author for this work

Research output: Contribution to journalArticleProfessional

Abstract

• Cyclosporine and infliximab are so-called 'rescue-therapies' as last resort for the treatment of patients with severe glucocorticoid-refractory ulcerative colitis. • A recent study found that cyclosporine and infliximab are similar in terms of efficacy in the treatment of patients with severe ulcerative colitis. • Cyclosporine may be prescribed as a bridge to treatment with thiopurines; infliximab may be prescribed when a patient is intolerant or refractory to thiopurines. • Preoperative treatment with cyclosporine or infliximab does not affect the number of postoperative complications.

Original languageDutch
Article numberA6130
JournalNederlands Tijdschrift voor Geneeskunde
Volume157
Issue number45
Publication statusPublished - 1 Dec 2013

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