Ongezonde leefstijl in de loop van het leven: Samenhang met lichamelijke achteruitgang op oudere leeftijd

Translated title of the contribution: Unhealthy lifestyles during the life course: Association with physical decline in late life

Saskia M.F. Pluijm*, M. Visser, M. T.E. Puts, M. G. Dik, B. W.M. Schalk, N. M. Van Schoor, L. A. Schaap, R. J. Bosscher, D. J.H. Deeg

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


This study aimed to examine the association between unhealthy lifestyle in young age, midlife and/or old age and physical decline in old age, and to examine the association between chronic exposure to an unhealthy lifestyle throughout life and physical decline in old age. The study sample included 1297 respondents of the Longitudinal Aging Study Amsterdam (LASA). Lifestyle in old age (55-85 y) was assessed at baseline, while lifestyle in young age (around 25 y) and midlife (around 40 y) were assessed retrospectively. Lifestyle factors included physical activity, body mass index (BMI), number of alcohol drinks per week and smoking. Physical decline was calculated as change in physical performance score between baseline and six-year follow-up. Of the lifestyle factors present in old age, a BMI of 25-29 vs. BMI < 25 kg/m2 (odds ratio (OR) 1.6; 95% confidence interval (CI) 1.1-2.2) and a BMI of ≥30 vs. BMI <25 kg/m2 (OR 1.8; 95% CI 1.2-2.7) were associated with physical decline in old age. Being physically inactive in old age was not significantly associated with an increased risk of physical decline, however, being physically inactive both in midlife and in old age increased the odds of physical decline in old age to 1.6 (95% CI 1.1-2.4) as compared to respondents who were physically inactive in midlife and physically active in old age. Being overweight in both age periods was associated with an OR of 1.5 (95% CI 1.1-2.2). These data suggest that overweight in old age, and chronic exposure to physical inactivity or overweight throughout life increases the risk of physical decline in old age. Therefore, physical activity and prevention of overweight at all ages should be stimulated to prevent physical decline in old age.

Original languageDutch
Pages (from-to)226-236
Number of pages11
JournalTijdschrift voor Gerontologie en Geriatrie
Issue number6
Publication statusPublished - 1 Dec 2006

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