Unusual complication after immediate postoperative intravesical Mitomycin C instillation

Jakko A. Nieuwenhuijzen; Axel Bex; Simon Horenblas

doi:10.1016/S0302-2838(03)00151-9

Unusual complication after immediate postoperative intravesical Mitomycin C instillation

Jakko A. Nieuwenhuijzen^*, Axel Bex, Simon Horenblas

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made.

Original language	English
Pages (from-to)	711-712
Number of pages	2
Journal	European Urology
Volume	43
Issue number	6
DOIs	https://doi.org/10.1016/S0302-2838(03)00151-9
Publication status	Published - 1 Jun 2003

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title = "Unusual complication after immediate postoperative intravesical Mitomycin C instillation",

abstract = "Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made.",

keywords = "Complications, Extravasation, Intravesical chemotherapeutics, Intravesical mitomycin C, Superficial bladder cancer",

author = "Nieuwenhuijzen, {Jakko A.} and Axel Bex and Simon Horenblas",

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AU - Nieuwenhuijzen, Jakko A.

AU - Bex, Axel

AU - Horenblas, Simon

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Y1 - 2003/6/1

N2 - Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made.

AB - Immediate adjuvant Mitomycin C (MMC) instillation is routine practice in the treatment of superficial bladder cancer. Despite relative safety we describe a case of MMC extravasation after intravesical instillation. This resulted in severe continuous pain in the pelvic region without tendency of spontaneous healing, and required surgical debridement. To assess perivesical soft tissue injury prior to surgery MRI imaging turned out to be more accurate than computer tomography. Suggestions about how to avoid, diagnose and treat this symptomatic extravasation are made.

KW - Complications

KW - Extravasation

KW - Intravesical chemotherapeutics

KW - Intravesical mitomycin C

KW - Superficial bladder cancer

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SN - 0302-2838

VL - 43

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JO - European Urology

JF - European Urology

IS - 6

ER -

Unusual complication after immediate postoperative intravesical Mitomycin C instillation

Abstract

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