Updating the psoriatic arthritis (PsA) core domain set: A report from the PsA workshop at OMERACT 2016

Ana Maria Orbai*, Maarten De Wit, Philip J. Mease, Kristina Callis Duffin, Musaab Elmamoun, William Tillett, Willemina Campbell, Oliver FitzGerald, Dafna D. Gladman, Niti Goel, Laure Gossec, Pil Hoejgaard, Ying Ying Leung, Chris Lindsay, Vibeke Strand, Désirée M. Van Der Heijde, Bev Shea, Robin Christensen, Laura Coates, Lihi EderNeil McHugh, Umut Kalyoncu, Ingrid Steinkoenig, Alexis Ogdie

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Full Release Article. For details see Reprints and Permissions at jrheum.org ABSTRACT. Objective. To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and longitudinal observational studies (LOS). Methods.At OMERACT 2016, research conducted to update the PsA Core Domain Set was presented and discussed in breakout groups. The updated PsA Core Domain Set was voted on and endorsed by OMERACT participants. Results. We conducted a systematic literature review of domains measured in PsA RCT and LOS, and identified 24 domains. We conducted 24 focus groups with 130 patients from 7 countries representing 5 continents to identify patient domains. We achieved consensus through 2 rounds of separate surveys with 50 patients and 75 physicians, and a nominal group technique meeting with 12 patients and 12 physicians. We conducted a workshop and breakout groups at OMERACT 2016 in which findings were presented and discussed. The updated PsA Core Domain Set endorsed with 90% agreement by OMERACT 2016 participants included musculoskeletal disease activity, skin disease activity, fatigue, pain, patient's global assessment, physical function, health-related quality of life, and systemic inflammation, which were recommended for all RCT and LOS. These were important, but not required in all RCT and LOS: economic cost, emotional well-being, participation, and structural damage. Independence, sleep, stiffness, and treatment burden were on the research agenda. Conclusion. The updated PsA Core Domain Set was endorsed at OMERACT 2016. Next steps for the PsA working group include evaluation of PsA outcome measures and development of a PsA Core Outcome Measurement Set.

Original languageEnglish
Pages (from-to)1522-1528
Number of pages7
JournalJournal of Rheumatology
Volume44
Issue number10
DOIs
Publication statusPublished - 1 Oct 2017

Cite this

Orbai, A. M., De Wit, M., Mease, P. J., Duffin, K. C., Elmamoun, M., Tillett, W., ... Ogdie, A. (2017). Updating the psoriatic arthritis (PsA) core domain set: A report from the PsA workshop at OMERACT 2016. Journal of Rheumatology, 44(10), 1522-1528. https://doi.org/10.3899/jrheum.160904