Validating rheumatoid arthritis remission using the patients' perspective: Results from a special interest group at OMERACT 2016

Linda A. Rasch*, Maarten Boers, Catherine L. Hill, Marieke Voshaar, Wijnanda Hoogland, Maarten De Wit, Caroline Flurey, Bev Davis, Merete Lund Hetland, Cecilie Heegaard Brahe, Laure Gossec, George A. Wells, Peter Tugwell, Bindee Kuriya, Niti Goel, Jasvinder A. Singh, Cátia Duarte, José Da Silva, Dirkjan Van Schaardenburg, Susanna ProudmanLilian H.D. Van Tuyl, Working Group on the Patients' Perspective on Remission in Rheumatoid Arthritis

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Objective. The Outcome Measures in Rheumatology (OMERACT) working group on the patients' perspective on remission in rheumatoid arthritis (RA) has been working on this topic since 2010. At OMERACT 2016, progress and preliminary data on validity of measurement instruments for pain, fatigue, and independence in remission in RA were presented, and future directions were explored. Methods.A special interest group was organized, in which the current data on the patients' perspective on remission were presented. The ongoing study that aimed to validate measurement instruments for pain, fatigue, and independence in a state of low disease activity or remission was presented, and preliminary data on construct validity and discriminative capacity were evaluated cross-sectionally. Results. At OMERACT 2016, the progress of the working group and preliminary data from 142 of the anticipated 300 patients were presented. Selected instruments significantly correlated with the Disease Activity Score in 28 joints (construct validity) and all instruments except 1 discriminated between patients in and patients not in remission. The subsequent discussion mainly focused around 3 points: (1) the formulation of patient perceived remission, (2) the duration of remission, and (3) the measurement of the domain independence. An informal vote indicated a slight preference for working toward modifying the current remission criteria by adding patient-reported outcomes (PRO), or by substituting the patient's global assessment with 1 or more PRO. Conclusion. More evidence on measuring patients' perspective on remission in RA is needed before an informed decision can be made regarding development or modification of remission definitions.

Original languageEnglish
Pages (from-to)1889-1893
Number of pages5
JournalJournal of Rheumatology
Issue number12
Publication statusPublished - 1 Dec 2017

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