Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting

Nanja van Geel, Albert Wolkerstorfer, Khaled Ezzedine, Amit G. Pandya, Marcel Bekkenk, Lynda Grine, Sarah van Belle, Janny E. Lommerts, Iltefat Hamzavi, John E. Harris, Viktoria Eleftheriadou, Samia Esmat, Hee Young Kang, Prasad Kumarasinghe, Cheng-Che E. Lan, Davinder Parsad, Noufal Raboobee, Leihong Flora Xiang, Tamio Suzuki, Cecilia A. PrinsenAlain Taieb, Mauro Picardo, Reinhart Speeckaert, the participants of the Rome International VGICC /VIS Workshop

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.
Original languageEnglish
Pages (from-to)728-733
JournalPigment Cell and Melanoma Research
Volume32
Issue number5
DOIs
Publication statusPublished - 1 Jan 2019

Cite this

van Geel, N., Wolkerstorfer, A., Ezzedine, K., Pandya, A. G., Bekkenk, M., Grine, L., ... the participants of the Rome International VGICC /VIS Workshop (2019). Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting. Pigment Cell and Melanoma Research, 32(5), 728-733. https://doi.org/10.1111/pcmr.12784