Vascular type of Ehlers-Danlos syndrome in a patient with a ruptured aneurysm of the splenic artery

P. W.B. Nanayakkara*, C. C. van Bunderen, S. Simsek, Y. M. Smulders, G. Pals

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

A 39-year-old woman presented with a ruptured aneurysm of the splenic artery. The postoperative course was complicated by poor wound healing. This, in combination with a history of easy bruising and joint hypermobility, made us consider a connective tissue disease as underlying cause. The vascular type of Ehlers-Danlos syndrome was diagnosed by identifying collagen III deficiency and the corresponding gene mutation in cultured fibroblasts from a skin biopsy.

Original languageEnglish
Pages (from-to)374-376
Number of pages3
JournalNetherlands Journal of Medicine
Volume64
Issue number10
Publication statusPublished - 1 Nov 2006

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