Ventilation and perfusion imaging by electrical impedance tomography: A comparison with radionuclide scanning

P. W.A. Kunst*, A. Vonk Noordegraaf, O. S. Hoekstra, P. E. Postmus, P. M.J.M. De Vries

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Electrical impedance tomography (EIT) is a technique that makes it possible to measure ventilation and pulmonary perfusion in a volume that approximates to a 2D plane. The possibility of using EIT for measuring the left-right division of ventilation and perfusion was compared with that of radionuclide imaging. Following routine ventilation (81mKr) and perfusion scanning (99mTc-MAA), EIT measurements were performed at the third and the sixth intercostal level in 14 patients with lung cancer. A correlation (r = 0.98, p < 0.005) between the left-right division for the ventilation measured with EIT and that with 81mKr was found. For the left-right division of pulmonary perfusion a correlation of 0.95 (p < 0.005) was found between the two methods. The reliability coefficient (RC) was calculated for estimating the left-right division with EIT. The RC for the ventilation measurements was 94% and 96% for the perfusion measurements. The correlation analysis for reproducibility of the EIT measurements was 0.95 (p < 0.001) for the ventilation and 0.93 (p < 0.001) for the perfusion measurements. In conclusion, EIT can be regarded as a promising technique to estimate the left-right division of pulmonary perfusion and ventilation.

Original languageEnglish
Pages (from-to)481-490
Number of pages10
JournalPhysiological Measurement
Issue number4
Publication statusPublished - 11 Dec 1998

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