Vitamin D Supplementation and Hemoglobin Levels in Hypertensive Patients: A Randomized Controlled Trial: International Journal of Endocrinology

J. B. Ernst, A. Tomaschitz, M.R. Grubler, M. Gaksch, K. Kienreich, N. Verheyen, W. Marz, S. Pilz, A. Zittermann

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Epidemiological evidence suggests that circulating 25-hydroxyvitamin D (25OHD) levels are inversely associated with hemoglobin (Hb) levels and anemia risk. We evaluated whether vitamin D supplementation improves Hb levels and reduces anemia risk in hypertensive patients. Two hundred patients with 25OHD levels 50 nmol/L. Themean (95% confidence interval) vitamin D effect on Hb levels was 0.04 (-0.14 to 0.22) g/dL (P = 0.661). Moreover, vitamin D treatment did not influence anemic status significantly (P > 0.999). Likewise, vitamin D had no significant effect on Hb levels in the subgroups of anemic patients or in patients with initial 25OHD levels
Original languageEnglish
Article number6836402
Number of pages7
JournalInternational Journal of Endocrinology
Publication statusPublished - 2016

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