Vitamine D niet zinvol voor alle 50-plussers

Translated title of the contribution: Vitamin D supplementation not useful for all older people

Yvonne H. M. Krul-Poel, Willem F. Lems, Renate T. de Jongh

Research output: Contribution to journalArticleProfessional


An estimated 1.5 million Dutch people take vitamin D supplements on prescription, not including those who take multivitamins or vitamin D over the counter. Yet, controversial health benefits of vitamin D supplementation in the general population continues, often explained with not adequately powered studies, combination therapy with calcium, high bolus doses of vitamin D and poor study designs. Recently, the VITAL study does not show an effect in fracture incidence after treatment with daily vitamin D (2000IU) compared to placebo. However, zooming into the results a positive trend is observed in patients with a fragility fracture and/or using anti-osteoporosis medication. Additionally this study does not rule out a positive effect of vitamin D supplementation in severe vitamin D deficiency and high fracture risk patients.
Translated title of the contributionVitamin D supplementation not useful for all older people
Original languageDutch
JournalNederlands Tijdschrift voor Geneeskunde
Publication statusPublished - 16 Mar 2023

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