@article{7e131367b0d744c9be9ceaa2cefff403,
title = "WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion",
abstract = "Benedict et al. show that in cancer cells the connection between newly synthesized chromatids (cohesion) is often less tight than in normal cells. They show that removal of cohesion in cancer cells is necessary to repair broken DNA replication forks and to sustain tumor cell expansion.",
keywords = "cohesinopathies, DNA double strand breaks, DNA repair, DNA replication stress, KRAS, oncogene-induced cohesion loss, RAD51, sister chromatid cohesion, STAG2, WAPL",
author = "Bente Benedict and {van Schie}, {Janne J.M.} and Oostra, {Anneke B.} and Balk, {Jesper A.} and Wolthuis, {Rob M.F.} and Riele, {Hein te} and {de Lange}, Job",
year = "2020",
month = mar,
day = "23",
doi = "10.1016/j.devcel.2020.01.024",
language = "English",
volume = "52",
pages = "683--698.e7",
journal = "Developmental Cell",
issn = "1878-1551",
publisher = "Cell Press",
number = "6",
}