Wave reflection and characteristic impedance in the conscious dog as influenced by adrenergic intervention

P. L M Kerkhof*, J. K J Li

*Corresponding author for this work

Research output: Contribution to conferencePaperAcademic

Abstract

The combined measurement of aortic root pressure, flow and diameter permits determination of e.g. arterial compliance (C) and characteristic impedance (Zo). These systemic circulatory properties reflect the dynamic load to the left ventricle. Obviously, it is of clinical interest to study possible effects of cardiopharmacologic intervention on C and Zo. Therefore, the specific aims of this study are first to delineate the characteristics of the systemic circulation and second to analyze the influence of adrenergic agonists and blockers on C and Zo. We investigate these questions in the chronically instrumented dog by analyzing in particular effects of alpha- and beta-adrenergic drugs. We found that on average Zo amounts to 0.11 mmHg.s/ml, while medetomidine (by a rise of approximately 70%) causes the largest increase in Zo.

Original languageEnglish
Pages107-108
Number of pages2
Publication statusPublished - 1 Dec 2001
Event23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Istanbul, Turkey
Duration: 25 Oct 200128 Oct 2001

Conference

Conference23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryTurkey
CityIstanbul
Period25/10/200128/10/2001

Cite this

Kerkhof, P. L. M., & Li, J. K. J. (2001). Wave reflection and characteristic impedance in the conscious dog as influenced by adrenergic intervention. 107-108. Paper presented at 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Istanbul, Turkey.