Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries 11 Medical and Health Sciences 1103 Clinical Sciences

Erik J. Timmermans, Elisa J. de Koning, Natasja M. van Schoor, Suzan van der Pas, Michael D. Denkinger, Elaine M. Dennison, Stefania Maggi, Nancy L. Pedersen, Ángel Otero, Richard Peter, Cyrus Cooper, Paola Siviero, Maria Victoria Castell, Florian Herbolsheimer, Mark Edwards, Federica Limongi, Dorly J. H. Deeg, Laura A. Schaap

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Abstract

Background: This study examines the association of both pain severity and within-person pain variability with physical activity (PA) in older adults with osteoarthritis (OA). Methods: Data from the European Project on OSteoArthritis were used. At baseline, clinical classification criteria of the American College of Rheumatology were used to diagnose OA in older adults (65-85 years). At baseline and 12-18 months follow-up, frequency and duration of participation in the activities walking, cycling, gardening, light and heavy household tasks, and sports activities were assessed with the Longitudinal Aging Study Amsterdam Physical Activity Questionnaire. Physical activity was calculated in kcal/day, based on frequency, duration, body weight and the metabolic equivalent of each activity performed. At baseline and 12-18 months follow-up, pain severity was assessed using the pain subscales of the Western Ontario and McMaster Universities OA Index and the Australian/Canadian Hand OA Index. Within-person pain variability was assessed using two-week pain calendars that were completed at baseline, 6 months follow-up and 12-18 months follow-up. Results: Of all 669 participants, 70.0% were women. Sex-stratified multiple linear regression analyses showed that greater pain severity at baseline was cross-sectionally associated with less PA in women (Ratio = 0.95, 95% CI = 0.90-0.99), but not in men (Ratio = 0.99, 95% CI = 0.85-1.15). The longitudinal analyses showed a statistically significant inverse association between pain severity at baseline and PA at follow-up in women (Ratio = 0.94, 95% CI = 0.89-0.99), but not in men (Ratio = 1.00, 95% CI = 0.87-1.11). Greater pain variability over 12-18 months was associated with more PA at follow-up in men (Ratio = 1.18, 95% CI = 1.01-1.38), but not in women (Ratio = 0.94, 95% CI = 0.86-1.03). Conclusions: Greater pain severity and less pain variability are associated with less PA in older adults with OA. These associations are different for men and women. The observed sex differences in the various associations should be studied in more detail and need replication in future research.
Original languageEnglish
Article number12
JournalBMC Musculoskeletal Disorders
Volume20
Issue number1
DOIs
Publication statusPublished - 2019

Cite this

Timmermans, Erik J. ; de Koning, Elisa J. ; van Schoor, Natasja M. ; van der Pas, Suzan ; Denkinger, Michael D. ; Dennison, Elaine M. ; Maggi, Stefania ; Pedersen, Nancy L. ; Otero, Ángel ; Peter, Richard ; Cooper, Cyrus ; Siviero, Paola ; Castell, Maria Victoria ; Herbolsheimer, Florian ; Edwards, Mark ; Limongi, Federica ; Deeg, Dorly J. H. ; Schaap, Laura A. / Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries 11 Medical and Health Sciences 1103 Clinical Sciences. In: BMC Musculoskeletal Disorders. 2019 ; Vol. 20, No. 1.
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title = "Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries 11 Medical and Health Sciences 1103 Clinical Sciences",
abstract = "Background: This study examines the association of both pain severity and within-person pain variability with physical activity (PA) in older adults with osteoarthritis (OA). Methods: Data from the European Project on OSteoArthritis were used. At baseline, clinical classification criteria of the American College of Rheumatology were used to diagnose OA in older adults (65-85 years). At baseline and 12-18 months follow-up, frequency and duration of participation in the activities walking, cycling, gardening, light and heavy household tasks, and sports activities were assessed with the Longitudinal Aging Study Amsterdam Physical Activity Questionnaire. Physical activity was calculated in kcal/day, based on frequency, duration, body weight and the metabolic equivalent of each activity performed. At baseline and 12-18 months follow-up, pain severity was assessed using the pain subscales of the Western Ontario and McMaster Universities OA Index and the Australian/Canadian Hand OA Index. Within-person pain variability was assessed using two-week pain calendars that were completed at baseline, 6 months follow-up and 12-18 months follow-up. Results: Of all 669 participants, 70.0{\%} were women. Sex-stratified multiple linear regression analyses showed that greater pain severity at baseline was cross-sectionally associated with less PA in women (Ratio = 0.95, 95{\%} CI = 0.90-0.99), but not in men (Ratio = 0.99, 95{\%} CI = 0.85-1.15). The longitudinal analyses showed a statistically significant inverse association between pain severity at baseline and PA at follow-up in women (Ratio = 0.94, 95{\%} CI = 0.89-0.99), but not in men (Ratio = 1.00, 95{\%} CI = 0.87-1.11). Greater pain variability over 12-18 months was associated with more PA at follow-up in men (Ratio = 1.18, 95{\%} CI = 1.01-1.38), but not in women (Ratio = 0.94, 95{\%} CI = 0.86-1.03). Conclusions: Greater pain severity and less pain variability are associated with less PA in older adults with OA. These associations are different for men and women. The observed sex differences in the various associations should be studied in more detail and need replication in future research.",
author = "Timmermans, {Erik J.} and {de Koning}, {Elisa J.} and {van Schoor}, {Natasja M.} and {van der Pas}, Suzan and Denkinger, {Michael D.} and Dennison, {Elaine M.} and Stefania Maggi and Pedersen, {Nancy L.} and {\'A}ngel Otero and Richard Peter and Cyrus Cooper and Paola Siviero and Castell, {Maria Victoria} and Florian Herbolsheimer and Mark Edwards and Federica Limongi and Deeg, {Dorly J. H.} and Schaap, {Laura A.}",
year = "2019",
doi = "10.1186/s12891-018-2392-0",
language = "English",
volume = "20",
journal = "BMC Musculoskeletal Disorders",
issn = "1471-2474",
publisher = "BioMed Central",
number = "1",

}

Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries 11 Medical and Health Sciences 1103 Clinical Sciences. / Timmermans, Erik J.; de Koning, Elisa J.; van Schoor, Natasja M.; van der Pas, Suzan; Denkinger, Michael D.; Dennison, Elaine M.; Maggi, Stefania; Pedersen, Nancy L.; Otero, Ángel; Peter, Richard; Cooper, Cyrus; Siviero, Paola; Castell, Maria Victoria; Herbolsheimer, Florian; Edwards, Mark; Limongi, Federica; Deeg, Dorly J. H.; Schaap, Laura A.

In: BMC Musculoskeletal Disorders, Vol. 20, No. 1, 12, 2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries 11 Medical and Health Sciences 1103 Clinical Sciences

AU - Timmermans, Erik J.

AU - de Koning, Elisa J.

AU - van Schoor, Natasja M.

AU - van der Pas, Suzan

AU - Denkinger, Michael D.

AU - Dennison, Elaine M.

AU - Maggi, Stefania

AU - Pedersen, Nancy L.

AU - Otero, Ángel

AU - Peter, Richard

AU - Cooper, Cyrus

AU - Siviero, Paola

AU - Castell, Maria Victoria

AU - Herbolsheimer, Florian

AU - Edwards, Mark

AU - Limongi, Federica

AU - Deeg, Dorly J. H.

AU - Schaap, Laura A.

PY - 2019

Y1 - 2019

N2 - Background: This study examines the association of both pain severity and within-person pain variability with physical activity (PA) in older adults with osteoarthritis (OA). Methods: Data from the European Project on OSteoArthritis were used. At baseline, clinical classification criteria of the American College of Rheumatology were used to diagnose OA in older adults (65-85 years). At baseline and 12-18 months follow-up, frequency and duration of participation in the activities walking, cycling, gardening, light and heavy household tasks, and sports activities were assessed with the Longitudinal Aging Study Amsterdam Physical Activity Questionnaire. Physical activity was calculated in kcal/day, based on frequency, duration, body weight and the metabolic equivalent of each activity performed. At baseline and 12-18 months follow-up, pain severity was assessed using the pain subscales of the Western Ontario and McMaster Universities OA Index and the Australian/Canadian Hand OA Index. Within-person pain variability was assessed using two-week pain calendars that were completed at baseline, 6 months follow-up and 12-18 months follow-up. Results: Of all 669 participants, 70.0% were women. Sex-stratified multiple linear regression analyses showed that greater pain severity at baseline was cross-sectionally associated with less PA in women (Ratio = 0.95, 95% CI = 0.90-0.99), but not in men (Ratio = 0.99, 95% CI = 0.85-1.15). The longitudinal analyses showed a statistically significant inverse association between pain severity at baseline and PA at follow-up in women (Ratio = 0.94, 95% CI = 0.89-0.99), but not in men (Ratio = 1.00, 95% CI = 0.87-1.11). Greater pain variability over 12-18 months was associated with more PA at follow-up in men (Ratio = 1.18, 95% CI = 1.01-1.38), but not in women (Ratio = 0.94, 95% CI = 0.86-1.03). Conclusions: Greater pain severity and less pain variability are associated with less PA in older adults with OA. These associations are different for men and women. The observed sex differences in the various associations should be studied in more detail and need replication in future research.

AB - Background: This study examines the association of both pain severity and within-person pain variability with physical activity (PA) in older adults with osteoarthritis (OA). Methods: Data from the European Project on OSteoArthritis were used. At baseline, clinical classification criteria of the American College of Rheumatology were used to diagnose OA in older adults (65-85 years). At baseline and 12-18 months follow-up, frequency and duration of participation in the activities walking, cycling, gardening, light and heavy household tasks, and sports activities were assessed with the Longitudinal Aging Study Amsterdam Physical Activity Questionnaire. Physical activity was calculated in kcal/day, based on frequency, duration, body weight and the metabolic equivalent of each activity performed. At baseline and 12-18 months follow-up, pain severity was assessed using the pain subscales of the Western Ontario and McMaster Universities OA Index and the Australian/Canadian Hand OA Index. Within-person pain variability was assessed using two-week pain calendars that were completed at baseline, 6 months follow-up and 12-18 months follow-up. Results: Of all 669 participants, 70.0% were women. Sex-stratified multiple linear regression analyses showed that greater pain severity at baseline was cross-sectionally associated with less PA in women (Ratio = 0.95, 95% CI = 0.90-0.99), but not in men (Ratio = 0.99, 95% CI = 0.85-1.15). The longitudinal analyses showed a statistically significant inverse association between pain severity at baseline and PA at follow-up in women (Ratio = 0.94, 95% CI = 0.89-0.99), but not in men (Ratio = 1.00, 95% CI = 0.87-1.11). Greater pain variability over 12-18 months was associated with more PA at follow-up in men (Ratio = 1.18, 95% CI = 1.01-1.38), but not in women (Ratio = 0.94, 95% CI = 0.86-1.03). Conclusions: Greater pain severity and less pain variability are associated with less PA in older adults with OA. These associations are different for men and women. The observed sex differences in the various associations should be studied in more detail and need replication in future research.

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UR - https://www.ncbi.nlm.nih.gov/pubmed/30611248

U2 - 10.1186/s12891-018-2392-0

DO - 10.1186/s12891-018-2392-0

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JO - BMC Musculoskeletal Disorders

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